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Glaucoma

Diffuse glaucomatous macular damage disproportionately associated with diminished facial recognition

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Diffuse glaucomatous macular damage is disproportionately associated with diminished facial recognition, considered as facial recognition scores at the 2% level of normal levels, according to a study in JAMA Ophthalmology.

In this prospective cohort study, 72 patients with glaucoma (144 eyes) with visual acuity of 20/40 or better in each eye, were included. Optic disc and macular spectral-domain optical coherence tomography and 10-2 visual field (VF) damage was used to categorize eyes with macular damage as having focal, diffuse, or mixed damage but only eyes with focal or diffuse damage were included in the study. Higher-acuity and lower-acuity eyes were determined by 10-2 VF mean deviation (MD).

Eyes with diffuse damage had greater contrast impairment compared with eyes with focal damage after adjusting for 10-2 VF MD, 24-2 VF MD, age, presence of an early cataract, and number of drops.

Patients with diffuse macular damage had significantly lower Cambridge Face Memory Test scores than those with macular damage, regardless of eye.

Reference
Hirji SH, Hood DC, Liebmann JM, et al. Association of patterns of glaucomatous macular damage with contrast sensitivity and facial recognition in patients with glaucoma. JAMA Ophthalmol. 2020; DOI:10.1001/jamaophthalmol.2020.4749.

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