Low-concentration nitrous oxide anesthesia beneficial during cataract surgery
Intraoperative anxiety and pain during cataract surgery were improved with 30% low-concentration nitrous oxide (N2O) anesthesia, which may lead to stabilization of intraoperative vital signs, according to a study.
In this single-center retrospective cohort study, 63 patients who underwent cataract surgery were included. A combination of local and N2O anesthesia (N2O group) was used on 39 patients (50 eyes), and 30 eyes of 24 patients received local anesthesia without N2O anesthesia (Air group) was used on 24 patients (30 eyes).
The change in the visual analogue scale (VAS) scores for anxiety and pain decreased significantly) in the N2O group compared with that in the Air group. There was no significant difference between groups in blood pressure changes. The change in heart rate decreased significantly in the N2O group compared with that in the Air group.
The change in anxiety level correlated significantly with patient age and preoperative VAS score for anxiety in the N2O group; in the Air group the change in anxiety level did not correlate with any factor.
Sasajima H, Zako M, Ueta Y, et al. Effects of Low-Concentration Nitrous Oxide Anesthesia on Patient Anxiety During Cataract Surgery: A Retrospective Cohort Study. Clin Ophthalmol. 2022;16:2803-2812. doi: 10.2147/OPTH.S382476. PMID: 36042911; PMCID: PMC9420443.