Combination drop preferred over standard drop regimen after cataract surgery

Patients who underwent cataract surgery, preferred a combination drop (prednisolone acetate 1%, gatifloxacin 0.5%, and bromfenac sodium 0.075%) compared to the same individual eye drop medications post-surgery, according to a study published in Clinical Ophthalmology.

“Post ocular surgery, patients are usually required to instill multiple topical drops to prevent infection, inflammation, and pain, often with a different bottle used for each drop,” said John Saharek, President of ImprimisRx, in a company press release. “For some patients this can be confusing and/or can be burdensome, which could lead to non-compliance and suboptimal health outcomes. ImprimisRx formulations such as LessDrops provide the unique ability to combine these individual ingredients into one bottle.”

In this prospective randomized study, 33 patients presenting for bilateral cataract surgery with contralateral eyes were randomly assigned to receive a combination therapy (prednisolone acetate 1%, gatifloxacin 0.5%, and bromfenac sodium 0.075%) or the same medications in separate drops (bromfenac sodium was 0.07%). Patients were examined on post-operative day 1, 15, and 30.

Changes in central macular thickness were similar between groups. No differences in visual acuity, corneal edema, cells or flare were observed between groups. One eye in the control group exhibited significant macular edema.

Patients said they preferred the combination drop.

Reference 

Solomon KD, Sandoval HP, Potvin R. Comparing combination drop therapy to a standard drop regimen after routine cataract surgery. Clin Opthalmol. 2020;14(1959-1965).