Patients with amblyopia who have neurodevelopmental delays had worse visual outcomes compared to patients without neurodevelopmental diagnoses, according to a poster presented at the 2021 AAPOS Virtual Meeting.
Patients with neurodevelopmental delays were also more likely to have residual amblyopia.
A total of 637 patients with amblyopia with an interocular difference in best-corrected visual acuity (IOD) of >/=2 lines were included in this study. A total of 66 patients with neurodevelopmental delays, including autism spectrum disorders, language/speech delay, behavioral disorders, and some genetic syndromes, were in the neurodevelopmental groups and 571 patients with amblyopia without a neurodevelopmental diagnosis were in the control group.
At the 12-18 month follow-up interval, patients in the neurodevelopmental group had worse amblyopic eye visual acuities (AEVA) and a smaller change in IOD than patients in the control group.
At the 12-18 month follow-up and final follow-up visits, 34% and 42% of patients in the neurodevelopmental group, respectively, had amblyopia resolution compared to 56% and 60%, respectively, in the control group.
Chinn RN, et al. Amblyopia treatment outcomes in patients with neurodevelopmental delay. Poster presented at: 2021 AAPOS Virtual Meeting.