1. Apr 09, 2021

Patients with amblyopia who have neurodevelopmental delays have worse visual outcomes

Patients with amblyopia who have neurodevelopmental delays had worse visual outcomes compared to patients without neurodevelopmental diagnoses, according to a poster presented at the 2021 AAPOS Virtual Meeting.

Patients with neurodevelopmental delays were also more likely to have residual amblyopia.

A total of 637 patients with amblyopia with an interocular difference in best-corrected visual acuity (IOD) of >/=2 lines were included in this study. A total of 66 patients with neurodevelopmental delays, including autism spectrum disorders, language/speech delay, behavioral disorders, and some genetic syndromes, were in the neurodevelopmental groups and 571 patients with amblyopia without a neurodevelopmental diagnosis were in the control group.

At the 12-18 month follow-up interval, patients in the neurodevelopmental group had worse amblyopic eye visual acuities (AEVA) and a smaller change in IOD than patients in the control group.

At the 12-18 month follow-up and final follow-up visits, 34% and 42% of patients in the neurodevelopmental group, respectively, had amblyopia resolution compared to 56% and 60%, respectively, in the control group.

Reference
Chinn RN, et al. Amblyopia treatment outcomes in patients with neurodevelopmental delay. Poster presented at: 2021 AAPOS Virtual Meeting.