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Glaucoma

This, Not Glaucoma, Appears to Be the Main Predictor of Macular Pigment

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Dietary habits appeared to be the main predictor of macular pigment (MP) volume in a cross-sectional study involving 107 individuals. The results challenge the notion that glaucoma is linked with low MP. 

Participants included patients with glaucoma (n=85) and healthy controls (n=22). Investigators took standard automated perimetry (SAP) and retinal nerve fiber layer (RNFL) thickness measurements. They also estimated lutein and zeaxanthin intake via a dietary screener, and evaluated the relationship between MP and glaucoma. Among the results: 

  • Glaucoma patients had significantly worse SAP measures and lower RNFL thickness than controls. 
  • MP volume was similar in both groups. 
  • Glaucoma diagnosis was not linked with MP volume.
  • Lutein and zeaxanthin intake were positively linked to MP volume.

Daga F, Ogata N, Medeiros F, et al. Macular pigment and visual function in patients with glaucoma: The San Diego Macular Pigment Study.  Invest Ophthalmol Vis Sci. 2018;59(11):4471-4476. doi: 10.1167/iovs.18-24170. 

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