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Glaucoma

This, Not Glaucoma, Appears to Be the Main Predictor of Macular Pigment

Posted on October 8, 2018

Dietary habits appeared to be the main predictor of macular pigment (MP) volume in a cross-sectional study involving 107 individuals. The results challenge the notion that glaucoma is linked with low MP. 

Participants included patients with glaucoma (n=85) and healthy controls (n=22). Investigators took standard automated perimetry (SAP) and retinal nerve fiber layer (RNFL) thickness measurements. They also estimated lutein and zeaxanthin intake via a dietary screener, and evaluated the relationship between MP and glaucoma. Among the results: 

  • Glaucoma patients had significantly worse SAP measures and lower RNFL thickness than controls. 
  • MP volume was similar in both groups. 
  • Glaucoma diagnosis was not linked with MP volume.
  • Lutein and zeaxanthin intake were positively linked to MP volume.

Daga F, Ogata N, Medeiros F, et al. Macular pigment and visual function in patients with glaucoma: The San Diego Macular Pigment Study.  Invest Ophthalmol Vis Sci. 2018;59(11):4471-4476. doi: 10.1167/iovs.18-24170. 

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