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TED severely impacts quality of life even when disease is stable

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Even after acute thyroid eye disease (TED) symptoms have subsided, patients still feel the physical and psychosocial impacts of the disease, according to a study that found TED severely impacts patient quality of life (QOL).

Of the 100 patients who took part in an online survey on chronic TED symptoms and patient QOL, 34% reported a high prevalence of anxiety, and 28% reported experiencing depression. On average, patients reported 20 doctor visits per year.

Participants had undergoing treatments including systemic corticosteroids during active TED (25%), orbital radiation (5%), and surgery (25%).

Overall Graves’ Ophthalmopathy QOL score, which takes into account overall; appearance; and vision-related QOL, was 60.5 ± 21.8. Hypothyroidism, anxiety, and more chronic TED symptoms were reported more frequently in patients with low QOL.

Patients with low QOL had more pain (39%), blurry vision (30%), and diplopia (27%) compared to patients with high QOL (13%, 17%, and 3%, respectively).

Participants with low QOL had more surgery related to TED, disability/unemployment, and doctor appointments.

Reference
Cockerham KP, Padnick-Silver L, Stuertz N, et al. Quality of Life in Patients with Chronic Thyroid Eye Disease in the United States. Ophthalmol Ther. 2021;doi: 10.1007/s40123-021-00385-8. Epub ahead of print. PMID: 34478126.

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