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Retina

AMD increases rate of mood disorders

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Having age-related macular degeneration (AMD) leads to an increased rate of mood disorders, with middle-aged participants, women, and those with dry-AMD experiencing the greatest rate, according to a study.

In this retrospective cohort study, 5916 patients with AMD and 11,832 individuals age- and sex-matched without AMD from the National Health Insurance Research Database (NHIRD) in Taiwan from 2000 and 2016, were included.

Amongst the AMD group, there were 1017 (17.19%) episodes of mood disorders; there were 1366 (11.54%) episodes in the group without AMD.

In patients with AMD, the adjusted hazard ratio of any psychological counseling, behavioral therapy, sleep or anxiety-related disorders, and major depressive disorders were significantly higher than in patients without AMD.

Patients with dry-AMD, participants aged 50-70 years, and women with AMD had a higher incidence of mood disorders than individuals without AMD, patients > 70 years, and women without AMD.

Reference
Lee CY, Chen HC, Huang JY, et al. Increased probability of mood disorders after age-related macular degeneration: a population-based cohort study. Sci Rep. 2022;12(1):15222. doi: 10.1038/s41598-022-19429-5. PMID: 36075924.

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