Corticosteroids for Bacterial Corneal Ulcers: Mixed Results
Using adjunctive topical corticosteroid therapy in eyes with bacterial corneal ulcers appears to be safe, according to a prospective, randomized, placebo-controlled trial involving 500 individuals. Such therapy might be particularly useful in eyes with severe ulcers or Pseudomonas infection. The findings were summarized in a recent article.
Primary outcomes of the trial were mixed (no change in best-corrected visual acuity at 3 months, but also no adverse events). An analysis of secondary outcomes shows situations where corticosteroids would be preferred and others where they should be avoided.
You can read more here.
Krader C, Lietman T. SCUT trial delves into corticosteroid role for bacterial corneal ulcers. Ophthalmology Times June 28, 2018.
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