Multifocal intraocular lenses (IOLs) implanted in Berger space can provide better visual outcomes and greater spectacle independence than traditional monofocal IOLs in children with cataracts, according to a study.
The study included 571 eyes from 402 pediatric patients who received either multifocal IOLs implanted in Berger space (n = 311 eyes) or monofocal IOLs with primary posterior capsulorhexis and anterior vitrectomy (n = 260 eyes).
Children who received multifocal IOLs showed significantly better distance and near visual acuity than those with monofocal lenses (P < 0.05). Depth perception also improved more frequently in the multifocal group. Modulation transfer function and Strehl ratio also increased after surgery in both groups, while ocular scatter decreased (P < 0.001), with no meaningful differences between unilateral and bilateral cases.
The researchers noted that multifocal IOL implantation resulted in higher rates of spectacle independence (51.7% vs 37.3%, P = 0.033). Implantation in Berger space was successful in over 93% of multifocal cases. Postoperative complication rates were low overall, but children receiving multifocal lenses experienced fewer cases of corneal edema, transient intraocular hypertension, and visual axis opacification compared with those given monofocal lenses (all P < 0.05).
Reference
Ding Y, Wan X, Kong L, et al. Multifocal versus Monofocal Intraocular Lens Implantation in Children with Cataracts. Am J Ophthalmol. 2025;S0002-9394(25)00487-8. doi: 10.1016/j.ajo.2025.09.017. Epub ahead of print. PMID: 40972859.
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