Kevin Yang Wu, MD, of the Université de Sherbrooke, spoke with Ophthalmology 360 at the 2026 ASCRS Annual Meeting about his study that found comparable efficacy outcomes between the Kahook Dual Blade MIGS technique versus the iStent inject technique.
Kevin Yang Wu MD:
Hello everyone. My name is Kevin Yang Wu, MD. I’m a resident physician from the Université de Sherbrooke in Canada. I’m a fourth-year resident. Thank you for inviting me for the speech.
Our study, it’s basically comparing the 2 different MIGS techniques: the KDB, which stands for Kahook Dual Blade MIGS technique versus the iStent inject technique, which is the second generation of the iStent MIGS.
Our study compared those 2, and then we found that both techniques, so the KDB versus the iStent are equally effective and efficient at reducing the IOP, the intraocular pressure. Our study’s primary endpoint, it’s a reduction of IOP of more than 20% and also less than 19 mmHg as defined for our primary outcome.
Both groups achieve quite a great result for those 2 primary outcomes. Then there’s no significant difference in that perspective. But we found that the KDB, so the Kahook Dual Blade, it has more adverse events and also a more failure rate, which is defined by the need for filtration surgery in the KDB group.
But the caveat is that in our study, the KDB group has more severe glaucoma, more advanced glaucoma compared to the iStent inject group. We have to interpret those results with caution. That’s pretty much of our study. Thank you very much for your time.
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