Study identifies key risk factors for proliferative vitreoretinopathy after retinal detachment

The main takeaway from this article is that both systemic factors and ocular factors significantly increase the risk of proliferative vitreoretinopathy (PVR) after rhegmatogenous retinal detachment (RRD), according to a study.

Researchers reviewed records from 57,264 eyes that underwent postoperative examinations within a month of RRD diagnosis. Cases with a history of proliferative diabetic retinopathy or pre-existing PVR were excluded.

Several significant risk factors for PVR were found. Systemic risks included younger age, female gender, smoking history, and hypertension. Ocular risks encompassed poor baseline visual acuity, prior ocular trauma, choroidal detachment, uveitis, giant retinal tears, pseudophakia, aphakia, and endophthalmitis.

The findings emphasize the need for ophthalmologists to account for these risk factors when planning surgeries and treatments for patients with RRD to minimize the risk of PVR development.

Reference
Oncel D, Minaker S, Shepherd EA, et al. Risk Factors for Proliferative Vitreoretinopathy in a Large Clinical Database. Retina. 2024;doi: 10.1097/IAE.0000000000004391. Epub ahead of print. PMID: 39752596.