1. Sep 28, 2020

Choroidal thickness may predictor for myopic maculopathy progression

Choroidal thickness (CT) is an independent predictor for myopic maculopathy progression, according to a study.

In this prospective, longitudinal, observational study, 434 participants between the ages of 7 and 70 years with bilateral high myopia (≤-6 D spherical error, range, −6 to −27.0 D) were followed for 2 years.

At baseline, mean age was 23.2±12.5 years, spherical equivalence was −10.50±3.18 D, and subfoveal CT (SFCT) was 153.20±72.76 μm.

Throughout the follow-up period, 17.1% (n = 74) of eyes had myopic maculopathy progression. In eyes with myopic maculopathy progression baseline SFCT was thinner than those without progression.

A multivariate logistic regression model showed that SFCT was a significant risk factor when age, gender, axial length, and baseline myopic maculopathy category were adjusted for

The predictive discrimination of myopic maculopathy progression was significantly improved when SFCT was added to established risk factors.