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IOLs
Presbyopia

Lab study looks at glare effects associated with diffractive optics in PCIOLs

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In a laboratory study investigation to characterize glare effects associated with diffractive optics in presbyopia-correcting intraocular lenses (PCIOLs), trifocal IOLs induced straylight (deg2sr-1) at lower angles, which may cause difficulties detecting these effects using a standard clinical approach. The latest IOL designs featuring chromatic aberration correction at far-focus appear more susceptible than the established trifocals to inducing glare phenomena, concluded the researchers.

The study was conducted at the David J. Apple Laboratory in Heidelberg, Germany, to quantify glare of IOLs using a diffractive principle to extend visual range and to identify models with increased susceptibility to inducing glare. Glare was assessed using straylight parameter with a standard C-Quant (Oculus GmbH) intended for 7° and 2 C-Quant modifications were used to test lower angles (ie, 2.5° and 3.5°). IOL models evaluated were: PanOptix (Alcon Inc.) and AT Lisa Tri (Zeiss Meditec) along with the Synergy (J&J Vision), and Triumf (BVI Medical), which had chromatic-aberration correction at distance. Straylight from trifocals was compared against a monofocal W-60R lens (Santen). The C-Quant test was performed through the studied IOLs via additional optical components attached to its ocular.

The results demonstrated straylight of the control was <1 at all tested angles, with the trifocal models showing comparable straylight at 7°. At 3.5°, Triumf’s straylight increased to 15.5 ±0.6, followed by Synergy (6.2 ±1.1), PanOptix (4.1 ±0.3), and AT Lisa Tri (2.0 ±0.8). The chromatic-aberration correcting models showed correspondingly high straylight (Synergy: 18.8 ±1.3; Triumf: 17.3 ±0.5) at 2.5° compared to PanOptix (4.3 ±0.4), AT Lisa Tri (2.1 ±0.1) and monofocal IOLs yielding minimal or no increase.

Reference
Łabuz G, Khoramnia R, Yan W, et al. Characterizing glare effects associated with diffractive optics in presbyopia-correcting intraocular lenses. J Cataract Refract Surg. January 16, 2024. doi:10.1097/j.jcrs.0000000000001398

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