A novel gonio-intervention combining excisional trabeculorhexis with uveoscleral outflow enhancement effectively reduces intraocular pressure (IOP) in patients with open-angle glaucoma undergoing cataract and uveoscleral intervention, according to a poster presented at AGS 2025.
In a study of 18 patients, successful intervention was achieved in all cases, with over 85% of patients experiencing trabecular excision beyond 120 degrees. No serious adverse events were reported.
After 12 months, the average IOP dropped from 21.6 mmHg to 12.1 mmHg, and medication reliance decreased. The combined approach, targeting both trabecular and uveoscleral outflow, resulted in sustained pressure control, highlighting its potential as an effective surgical option for OAG management.
Reference
Yadgarov A, et al. Circumferential goniotomy with superelastic microfilament as adjunct to bio-interventional uveoscleral surgery for dual-outflow IOP lowering. Poster presented at: American Glaucoma Society Annual Meeting; February 26–March 2, 2025; Washington, DC.
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