Phaco-KDB surgery provides long-term IOP reduction and medication relief in glaucoma patients
Kahook Dual Blade goniotomy with cataract surgery (phaco-KDB) surgery effectively lowers intraocular pressure (IOP) and reduces the need for glaucoma medications for up to three years, with better outcomes in patients who have not had prior laser trabeculoplasty (LTP) and those with pseudoexfoliative or pigmentary glaucoma, according to a poster presented at AGS 2025.
The retrospective study included 91 eyes with various forms of glaucoma. At 3 years post-surgery, 58.6% of eyes met the success criteria, with LTP-naïve eyes demonstrating better outcomes (62.3%) compared to those with prior LTP (43.8%). LTP was identified as a significant risk factor for reoperation. Mean IOP decreased significantly from 17.4 mmHg preoperatively to 13.8 mmHg at 2.5 years post-op, with greater reductions observed in patients with pseudoexfoliative or pigmentary glaucoma. Medication use was also reduced through 3 years.
Reference
Claxton MR, et al. Kahook Dual Blade Goniotomy with Cataract Extraction: How Laser Trabeculoplasty and Glaucoma Sub-Type Affect Outcomes. Poster presented at: American Glaucoma Society Annual Meeting; February 26–March 2, 2025; Washington, DC.
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