Study finds low rate of infections following glaucoma surgery, with no cases linked to MIGS
Serious infections following glaucoma surgery are rare, especially with minimally invasive glaucoma surgeries (MIGS), which had no reported cases of endophthalmitis during the 13-year study period, according to a presentation at the 2025 ASCRS Annual Meeting.
Researchers analyzed 12,115 procedures performed between 2010 and 2023, including trabeculectomy, glaucoma drainage device (GDD) implantation, MIGS, and other surgical techniques.
GDD implantation was the most common procedure, followed by trabeculectomy. The study identified cases of endophthalmitis in ≤1% of trabeculectomy patients and 0.2% of those receiving GDDs. Only 1 case was reported following Xen gel stent implantation, while no infections were linked to MIGS procedures during the study period.
Despite the overall low risk of infection, GDD-related complications due to tube malposition or erosion occurred in 10.2% of cases. The findings highlight the relatively low incidence of serious post-surgical infections and suggest that MIGS may carry a particularly favorable safety profile.
Reference
Adetunji MO, et al. Infections Following Glaucoma Incisional Surgery, Minimally Invasive Glaucoma Surgery, and Cycloablative Procedures: A Retrospective Review. Presented at: American Society of Cataract and Refractive Surgery Annual Meeting; April 25–28, 2025; Los Angeles, CA.
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