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Cornea and External Disease

Drug use–related endogenous endophthalmitis hospitalizations increase

Posted on November 10, 2020

From 2003 to 2016, the rate of drug use–related endogenous endophthalmitis hospitalizations increased 4-fold in the United States, according to a study.

In this retrospective cross-sectional study, 56,839 patients admitted with a diagnosis of endogenous endophthalmitis from 2003 to 2016 were included. Of these patients, 13.7% (n = 7783) had a history of drug dependence or use. Patients who had a history of drug use were significantly younger and more likely to be men.

Endogenous endophthalmitis incidence associated with drug use increased from 0.08 per 100 000 in 2003 to 0.32 per 100 000 population in 2016

The incidence of endogenous endophthalmitis associated with drug dependence or use increased from 0.08 per 100,000 in 2003 to 0.32 per 100,000 population in 2016 across the United States.

The authors concluded that “clinicians should maintain a high index of suspicion for endophthalmitis when evaluating patients with intraocular inflammation in the setting of drug dependence or use.

Reference

Mir TA, Papudesu C, Fang W, et al. Incidence of drug use–related endogenous endophthalmitis hospitalizations in the United States, 2003 to 2016. JAMA Ophthalmol. Published online November 05, 2020. DOI:10.1001/jamaophthalmol.2020.4741

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