Does having wet AMD effect COVID-19 outcomes?

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Patients with wet AMD may be at a greater risk of susceptibility to severe clinical outcomes of COVID-19, according to a study.

In this Korean nationwide cohort, data from all patients >40 years who underwent SARS-CoV-2 testing in South Korea from January 1, 2020, and May 15, 2020, were included.

Of the 135,435 patients who were tested for SARS-CoV-2 in the unmatched cohort, 4531 (3.3%) tested positive for SARS-CoV-2 and 5493 (4.1%) patients had AMD.

Researchers found that wet AMD was associated with an increased likelihood of susceptibility to SARS-CoV-2 infection and a “considerably greater risk” of severe clinical outcomes of COVID-19. No association was found with non-wet AMD.

Yang JM, Moon SY, Lee JY, et al. COVID-19 morbidity and severity in patients with age-related macular degeneration: a Korean nationwide cohort study. Am J Ophthalmol. 2021; DOI:https://doi.org/10.1016/j.ajo.2021.05.024

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