Do males and females with central retinal vein occlusions present with different features?

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Presenting features of patients with central retinal vein occlusions (CRVO) differ according to sex, according to a study.

In this retrospective, longitudinal cohort study the charts of 476 patients with CRVO were reviewed. The average age of onset of CRVO was 63.8 years in males compared with 66.1 years (P = 0.048). At 12 months, ischemic CRVO was more common in males compared to females (54% vs 45%, P = 0.05), and at baseline and final visits, central subfield thickness was greater in males versus females. In addition, males were more likely to have Foveal avascular zone enlargement (38% vs 25%, P = 0.04).


Mirzania D, Thomas AS, Rothman AL, et al. Sex differences in presentation, treatment patterns, and clinical outcomes in central retinal vein occlusion. Ophthalmic Surg Lasers Imaging Retina. 2020;51(5):279-285https://doi.org/10.3928/23258160-20200501-05.

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