Facial dermal collarettes may be an indicator for demodex mites

The presence of dermal collarettes on the face correlates significantly with the presence of demodex mites on microscopic examination of eyelashes, according to a poster presented at ASCRS 2024. The study found that dermal collarettes have a high positive predictive value (PPV) for indicating demodex mites, with a PPV of 78% and a sensitivity of 87%. This suggests that incorporating a quick evaluation for dermal collarettes during routine anterior segment clinical exams could aid in the diagnosis of demodex infestation, potentially facilitating earlier detection and treatment.

The research, encompassing 119 patient cases since January 1, 2023, on several key factors, including the presence of dermal collarettes (known as the alpenglow sign), the presence and density of mites on microscopic examination of epilated lashes, and the presence of eyelash collarettes.

Of the patients reviewed, 58% exhibited a positive alpenglow sign, indicating the presence of dermal collarettes on the face. Moreover, 68.1% of patients were found to have demodex mites upon microscopic examination of eyelashes.

The positive predictive value of dermal collarettes for demodex mites was 78%, with a sensitivity of 87%.

The researchers concluded that the presence of dermal collarettes, easily observable during routine anterior segment clinical examinations, could potentially expedite the diagnosis of demodex infestation.

Reference
Periman L, et al. Positive Predictive Value of Dermal Collarettes (Alpenglow Sign) for Demodex Mites on Microscopic Exam: A Retrospective Chart Analysis. Poster presented at: ASCRS Annual Meeting 2024.