Micropulse transscleral laser lowers IOP in silicone oil-induced glaucoma

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Micropulse transscleral laser therapy (MP-TLT) was found to effectively lower intraocular pressure (IOP) in patients with uncontrolled silicone oil-induced glaucoma (SOG), according to a study.

In this prospective case series, 33 eyes with uncontrolled SOG were treated with MP-TLT using the IRIDEX Cyclo G6 Glaucoma Laser System with the MicroPulse P3 fiberoptic handheld probe and followed for 1 year. The mean age of the 33 patients included in the study was 50.39 years old.

In 22 cases, silicone oil tamponade was indicated for complicated rhegmatogenous retinal detachment. The remaining cases included diabetic tractional retinal detachment (n = 10) and posttraumatic retinal detachment (n = 1).

Silicone oil was had been removed prior to the procedure in 23 eyes. Silicone oil tamponade duration varied between 3 and 26 months

IOP measurements were as follows:

Baseline: 37.94±13.61 mm Hg
Day 1: 19.03±10.98 mm Hg
Day 7: 16.5±6.17 mm Hg
Day 15: 19.45±9.73 mm Hg
Month 1: 19.27±8.33 mm Hg
Month 3: 19.39±9.52 mm Hg
Month 6: 19.97±10.03 mm Hg
Month 12: 19.7±9.58 mm Hg

At 6 months and 12 months, IOP was lowered 45.38% and 45%, respectively. The success rate was 93.93% at 6 months and remained stable at 12 months.

No major side effects were reported.

There was no difference in IOP reduction between patients with silicone oil or those after silicone oil removal.

Zbiba W, Sayadi S, Kharrat M, et al. Efficacy and Safety of Micropulse Transscleral Laser Therapy in Silicone Oil-induced Glaucoma. J Glaucoma. 2022;31(8):689-693. doi: 10.1097/IJG.0000000000002051. Epub 2022 May 10. PMID: 35583509.