More than 60 drugs linked with acute angle closure

A new case-crossover study analyzing the prescription records of 13,531 patients with acute angle closure (AAC), found that 61 drugs, including sumatriptan, topiramate, and duloxetine, were associated with AAC. The study, published in JAMA Ophthalmology, also noted that drugs not previously associated with ACC were identified, including lactulose and metoclopramide.

The median period from prescription of the drug to the onset of AAC was 11.9 days.

Reference
Na KI, Park SP. Association of Drugs With Acute Angle Closure. JAMA Ophthalmol. Published online September 22, 2022. doi:10.1001/jamaophthalmol.2022.3723