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Glaucoma
Journal Scan

OMNI surgical system significantly reduces IOP at 24 months in patients with OAG

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Patients with uncontrolled mild to moderate open-angle glaucoma had significant reductions in intraocular pressure (IOP) and medications at 24 months following trabeculotomy/viscodilation using the OMNI surgical system (Sight Sciences, Inc), according to a study.

In this retrospective analysis, 38 eyes (27 patients) with uncontrolled open-angle glaucoma were included. Patients underwent 360° viscodilation followed by up to 360° trabeculotomy as a standalone procedure. IOP and medication data were collected before surgery through 24 months.

The mean baseline IOP was 24.6 mmHG and reduced to 12.6 to 14.9 mmHg through 24 months. At 24 months, mean IOP was 14.9 mmHg and all eyes achieved IOP reduction > 20% from baseline.

The mean baseline medications were 1.9 and reduced to 0.0 -0.5 through 24 months. At 24 months, mean medication use was 0.5, and 84.6% of eyes were using > 1 fewer medication whereas 57.7% were medication-free.

The most common adverse event was intraoperative hyphema, which occurred in 44.7%, and resolved spontaneously in all cases.

Reference
Klabe K, Kaymak H. Standalone Trabeculotomy and Viscodilation of Schlemm’s Canal and Collector Channels in Open-Angle Glaucoma Using the OMNI Surgical System: 24-Month Outcomes. Clin Ophthalmol. 2021;15:3121-3129. https://doi.org/10.2147/OPTH.S325394

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