Study compares 180° vs 360° SLT in open angle glaucoma

Compared to 180° selective laser trabeculoplasty (SLT), 360° SLT produces greater intraocular pressure (IOP) lowering effects at 1 year in patients with open angle glaucoma and glaucoma suspects, according to a study.

In this single-center randomized control trial, 40 patients (80 eyes) presenting with treatment naïve open angle glaucoma or suspected glaucoma, had 1 eye randomized to 180° SLT and the other to 360° SLT.

After 1 year, IOP was reduced from 25.3±2.3 mmHg to 21.5±2.7 mmHg and 25.5±2.1 mmHg to 19.9±2.6 mmHg (P < 0.01), in the 180° and 360° groups, respectively.

There was no significant difference in the number of adverse events or serious adverse, differences in VA, Humphrey visual field mean deviation, RNFL thickness, or C:D ratio at the 1-year follow-up between the groups.

Reference
Michaelov E, Sachdeva R, Raniga A, et al. A Randomized, Controlled Comparison of 180° vs. 360° Selective Laser Trabeculoplasty (SLT) in Open Angle Glaucoma and Glaucoma Suspects. J Glaucoma. 2023;doi: 10.1097/IJG.0000000000002184. Epub ahead of print. PMID: 36795531.