Study highlights long-term outcomes of OMNI Surgical System for POAG
Standalone canaloplasty and trabeculotomy using the OMNI Surgical System is an effective minimally invasive glaucoma surgery (MIGS) option for patients with primary open-angle glaucoma (POAG), providing sustained reductions in intraocular pressure (IOP) and, in some cases, medication use over 36 months of follow-up, according to a study.
The retrospective cohort study analyzed data from the American Academy of Ophthalmology’s IRIS Registry, including 230 eyes from 196 patients with primary open-angle glaucoma (POAG) or ocular hypertension who underwent treatment and were followed for up to 36 months postoperatively. Eyes with prior filtration surgery, recent trabeculoplasty, or combined cataract surgery were excluded.
Key Findings:
- Intraocular Pressure: Mean baseline IOP was 22.1 mmHg, with reductions to 15.1–16.7 mmHg over 36 months (P < 0.0001). Eyes with higher baseline IOP (>18 mmHg) experienced significant, sustained reductions throughout the follow-up.
- Medication Use: Baseline use of 2.1 medication classes decreased to 1.1–1.8 classes over 36 months, with significant reductions maintained through 18 months (P ≤ 0.0011). Eyes with lower baseline IOP (≤18 mmHg) saw sustained reductions in medication use.
- Patient Demographics: Most eyes had moderate to severe POAG, with 44.4% of procedures performed by glaucoma specialists.
The findings support standalone OMNI surgery as a MIGS option for patients seeking to lower IOP, reduce medication dependence, or both.
Reference
Radcliffe NM, Harris J, Garcia K, et al. Standalone Canaloplasty and Trabeculotomy Using the OMNI Surgical System in Eyes with Primary Open-Angle Glaucoma: A 36-Month Analysis from the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight): Standalone Outcomes of Canaloplasty and Trabeculotomy. Am J Ophthalmol. 2024;S0002-9394(24)00581-6. doi: 10.1016/j.ajo.2024.12.015. Epub ahead of print. PMID: 39722265.
