Higher asphericity of lenslets may control myopia more than conventional lenses

Spectacle lenses with highly aspherical lenslets (HAL) and spectacle lenses with slightly aspherical lenslets (SAL) reduced the rate of myopia progression and axial elongation over 2 years, according to a study.

In this double-masked randomized clinical trial, data from 157 children aged 8 to 13 years with a cycloplegic spherical equivalent refraction (SER) of −0.75 D to −4.75 D and astigmatism with less than −1.50 D randomized to receive spectacle lenses with HAL (n = 54), SAL (n = 53), or SVL (n = 50) were analyzed. Changes in SER and axial length over 2 years were recorded.

In the SVL group, the mean (SE) 2-year myopia progression was 1.46 (0.09) D and the mean (SE) increase in axial length was 0.69 (0.04) mm. The mean (SE) change in SER was less for HAL (by 0.80 [0.11] D) and SAL (by 0.42 [0.11] D; P ≤ 0 .001) when compared with SVL. The increase in axial length was slowed by a mean (SE) of 0.35 (0.05) mm for HAL and 0.18 (0.05) mm for SAL (P ≤ 0.001) when compared with SVL.

Longer wearing hours– at least 12 hours every day– resulted in better myopia control efficacy for HAL compared with SVL.

Reference
Bao J, Huang Y, Li X, et al. Spectacle Lenses With Aspherical Lenslets for Myopia Control vs Single-Vision Spectacle Lenses: A Randomized Clinical Trial. JAMA Ophthalmol. Published online March 31, 2022. doi:10.1001/jamaophthalmol.2022.0401