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Inherited Retinal Disease

Blindness severity increases worldwide: key findings call for enhanced eye care strategies

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The global burden of blindness has increased over recent decades, primarily due to rising disease severity in specific conditions, according to a new study. This trend highlights a gap between life expectancy and healthy vision, underscoring the need for preventive and long-term treatment strategies to improve visual health outcomes, especially among women and in lower-income regions.

The study examined how the burden of blindness has evolved from 1990 to 2019, focusing on cause-specific changes in disease severity. Researchers utilized data from the Global Burden of Disease 2019 study to evaluate blindness trends across 18 different causes. By analyzing prevalence, disability-adjusted life-years (DALYs), and demographic changes, the study assessed how factors like population growth, aging, and disease severity impacted blindness globally.

Key findings from the study include:

  • Rising DALYs: The global burden of blindness, measured in DALYs, has increased from 1990 to 2019, with higher rates observed in women than men.
  • Gender Disparity: Women experienced a greater increase in DALYs related to blindness compared to men.
  • Cause-Specific Increases: The primary causes of increased blindness burden globally were cataracts, refractive errors, and glaucoma.
  • Regional Variations: Age-related macular degeneration was a leading contributor in high-income regions, while trachoma and retinopathy of prematurity were more prominent in lower-income regions.

The study indicates a need for preventive and sustained treatment measures to improve visual health outcomes.

Reference
Chen J, Chen X, Zhu Y, et al. Quantifying the impact of disease severity changes on the burden of blindness: A global decomposition analysis. J Glob Health. 2024;14:04248. doi: 10.7189/jogh.14.04248. PMID: 39485018; PMCID: PMC11529148.

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