Botulinum toxin injections are a possible alternative to surgical repair to temporarily manage ptosis in patients, according to a study.
In this prospective study, 8 patients with mild to moderate ptosis received botulinum neurotoxin A injection into the orbicularis oculi muscle for the management of blepharoptosis.
Patients were assessed at baseline, 2 weeks, 4 weeks, and 24 weeks for margin reflex distance -1 (MRD-1) and qualitative changes on a 4-point scale.
At week 2 there was a significant increase in the MRD-1 on the treated side (2.52 ± 1.13 mm) and a significant reduction on the contralateral eyelid (3.07 ± 0.96) compared to baseline (2.00 ± 1.13 mm and 3.23 ± 0.92 mm, respectively)
After 24 weeks there was no significant difference from baseline in either eyelid.
Approximately 88% of patients said they noticed an improvement in their eyelid ptosis.
Reference
Ludwig GD, Osaki MH, Gameiro GR, et al. Is It Worth Using Botulinum Toxin Injections for the Management of Mild to Moderate Blepharoptosis? Aesthet Surg J. 2022;sjac139. doi: 10.1093/asj/sjac139. Epub ahead of print. PMID: 35657738.
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