Reliable visual acuity analysis in presbyopia achieved with fewer measurements

Visual acuity curve (VAC) and its area (AoC) in presbyopia correction can be achieved with as few as 4 visual acuity (VA) measurements if taken at specific optimal distances, thanks to mathematical modeling using cubic spline interpolation, according to a study.

The study included 120 participants who underwent bilateral premium intraocular lens (IOL) implantation. Postoperative VA was measured at 9 predefined distances, and a mathematical model using cubic spline interpolation was developed to predict VAC and AoC values using a subset of these measurements.

Results showed that fewer than 4 measurements were insufficient for reliable estimation. However, 4 to 6 measurements taken at optimal distances produced accurate predictions, with a mean error ranging from 2.54 letters/1.74% (6 measurements) to 2.90 letters/2.9% (4 measurements).

Reference
Labiris G, Bakirtzis M, Panagis C, et al. Revisiting the Visual Acuity Curves. A Proposed Methodology for the Evaluation of Postoperative Visual Acuity in Presbyopia. Clin Ophthalmol. 2024;18:3935-3947. doi: 10.2147/OPTH.S487400. PMID: 39790982; PMCID: PMC11714096.