44.210.77.106
dgid:
enl:
npi:0
-Advertisement-
-Advertisement-
Retina

Cost-Effectiveness of Wet AMD Treatments Analyzed

Posted on

In the treatment of wet age-related macular degeneration, aflibercept injection appears to be just as effective as ranibizumab when the latter is administered monthly, but it is less costly, according to a recent analysis. Meanwhile, aflibercept costs more than ranibizumab when the latter is given as needed, but it appears to be more effective.

Investigators conducted a Markov cohort model analysis to estimate the lifetime quality-adjusted life-years (QALYs) and costs of treating patients with aflibercept injection 2 mg every 8 weeks after 3 initial monthly doses, vs ranibizumab 0.5 mg either monthly or as needed. Analyzing data from the VIEW 1, VIEW 2, and Comparison of AMD Treatments Trials, researchers looked at best-corrected visual acuity change, as well the impact of blindness on mortality.

When ranibizumab was administered monthly:

  • Both medications offered similar QALYs (5.44)
  • Aflibercept cost a total of ~$33,750 vs. $48,000 for ranibizumab PRN.

When ranibizumab was administered as needed:

  • Aflibercept yielded slightly greater QALYs (5.44 vs. 5.40).
  • Ranibizumab’s total cost of ~$33,650 was slightly less than the cost of aflibercept, with an incremental cost per QALY gained of nearly $2,600.

Hernandez L, Lantis T, Cele C, Toro-Diaz H, Kuznik A. Intravitreal aflibercept versus ranibizumab for wet age-related macular degeneration: A cost-effectiveness analysis. J Manag Care Spec Pharm. 2018;24(7):608-616. doi: 10.18553/jmcp.2018.24.7.608.

-Advertisement-
Related Articles
Wearable collision warning device helps visually impaired individuals
Jul 22, 2021
Psoriasis linked with significantly higher risk of retinal diseases
Jul 20, 2021
Ranibizumab biosimilar has comparable efficacy, safety profile to reference product in patients with nAMD
Jul 19, 2021
-Advertisement-
-Advertisement-
-Advertisement-
-Advertisement-
-Advertisement-