Cooling anesthesia device reduces pain during intravitreal injections
A cooling anesthesia device reduced pain associated with intravitreal injections in a multicenter clinical trial, with the lowest pain scores observed when the device was applied at -15°C for 10 seconds. The open-label, dose-escalation study enrolled 80 patients who had previously received at least 3 intravitreal injections and had used subconjunctival lidocaine for anesthesia. Participants... ...