AS-OCT shown to be a reliable alternative to gonioscopy for angle triage
Specialist-reviewed anterior segment optical coherence tomography (AS-OCT) can safely and effectively replace gonioscopy as a triage tool for angle assessment in virtual glaucoma clinics, according to a study.
Researchers at Sheffield Teaching Hospital evaluated 384 eyes referred to their glaucoma service over a 5-month period, using both AS-OCT and gonioscopy to determine whether angles were open or closed. Trained ophthalmic science practitioners performed gonioscopy, and 2 glaucoma subspecialists independently reviewed AS-OCT images.
Of the 358 eyes analyzed, AS-OCT demonstrated a high sensitivity (97.1%) and strong positive predictive value (95.7%) for identifying open angles, though specificity was lower (36.2%). The researchers concluded that AS-OCT, when interpreted by glaucoma specialists, is a safe and effective triage method.
Reference
Dhalla A, Evans T, Pilling J, et al. Comparison of anterior segment optical coherence tomography versus technician led gonioscopy as a triage tool for anterior chamber angle status. Eye (Lond). 2025;doi: 10.1038/s41433-025-03906-y. Epub ahead of print. PMID: 40624244.