Cataract surgery rates impact angle closure prevalence in older patients

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When cataract surgery rates (CSR) increased, occludable angle (OA) prevalence decreased in an older population with primary angle-closure glaucoma (PACG), according to a study published in the Journal of Glaucoma.

In this study, data of the right eye from 1280 patients ≥50 years old were included. Prior to dilation, OA was evaluated by static gonioscopy and anterior chamber depth.

Fifty cohorts (n = 200) generated by random sampling were created for each predefined CSR at 2,000, 4.000, 6.000, 8.000, 10.000, 12,000, according to the multinomial distribution.

The prevalence of cataract surgery was 2.27% and the prevalence of OA 11.3%.

The projected prevalence of OA in the cohorts are below:

  • 2000 was 11.4% 95% CI, 10.8%- 12.0%
  • 4000 was 11.2% 95% CI, 10.6%-11.9%
  • 6000 was 10.9% 95% CI, 10.3%-11.6%
  • 8000 was 11.4% 95% CI, 10.8%-12.1%
  • 10000 was 10.8% 95% CI, 10.2-11.4%
  • 12000 was 10.1% 95% CI, 9.46-10.7%

The authors noted that the prevalence of OA decreased “remarkably” as CSR increased for participants 70 years old.

They concluded that cataract surgery should be performed “at an appropriate time for patients in their late sixties to seventies with significant cataracts.

Jin G, Wang L, Scheetz J, Zhang J, He M. How does cataract surgery rate affect angle closure prevalence. J Glaucoma. 2020 Oct 7. doi: 10.1097/IJG.0000000000001691. Epub ahead of print. PMID: 33031186.

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