This, Not Glaucoma, Appears to Be the Main Predictor of Macular Pigment

Posted on

Dietary habits appeared to be the main predictor of macular pigment (MP) volume in a cross-sectional study involving 107 individuals. The results challenge the notion that glaucoma is linked with low MP. 

Participants included patients with glaucoma (n=85) and healthy controls (n=22). Investigators took standard automated perimetry (SAP) and retinal nerve fiber layer (RNFL) thickness measurements. They also estimated lutein and zeaxanthin intake via a dietary screener, and evaluated the relationship between MP and glaucoma. Among the results: 

  • Glaucoma patients had significantly worse SAP measures and lower RNFL thickness than controls. 
  • MP volume was similar in both groups. 
  • Glaucoma diagnosis was not linked with MP volume.
  • Lutein and zeaxanthin intake were positively linked to MP volume.

Daga F, Ogata N, Medeiros F, et al. Macular pigment and visual function in patients with glaucoma: The San Diego Macular Pigment Study.  Invest Ophthalmol Vis Sci. 2018;59(11):4471-4476. doi: 10.1167/iovs.18-24170. 

Related Articles
IOP outcomes after laser trabeculoplasty in eyes with prior Kahook Dual Blade goniotomy limited
Jul 28, 2021
Hydrus microstent reduces IOP, medication burden
Jul 26, 2021
IOP, gel microstents complications leading cause of reoperation after MIGS
Jul 23, 2021