These OCT Maps Detected Progression in Eyes with Early Glaucoma

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Analyzing specific combined wide-field optical coherence tomography (OCT) maps accurately detected structural progression in eyes with early glaucoma, according to a retrospective observational study involving 94 individuals. 

Participants were an average of 51 years of age with primary open-angle glaucoma who were followed for at least 3 years. Investigators divided them into nonprogressor (n=47) and progressor (n=47) groups. OCT maps integrating parapapillary retinal nerve fiber layer (RNFL) and macular ganglion cell–inner plexiform layer (GCIPL) were generated. Glaucoma specialists then assessed the diagnostic ability of the OCT maps to detect early glaucoma progression. Among the results: 

  • The OCT map analysis showed good agreement for detection of structural progression between the 2 glaucoma graders.
  • These maps showed early glaucomatous structural progression detection abilities comparable with those of RNFL and GCIPL GPAs. 

Lee W, Kim T, Kim T, Jeoung J, Park K. Serial Combined wide-field optical coherence tomography maps for detection of early glaucomatous structural progression. JAMA Ophthalmol. 2018;136(10):1121-1127. doi: 10.1001/jamaophthalmol.2018.3160.

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