Corneal biomechanics linked to myopia severity

Biomechanical parameters may be valuable in predicting scleral strength and have potential applications in the clinical management of high myopia, according to a study.

A recent study explored the relationship between corneal biomechanical properties and different levels of myopia using the Corvis ST device. The research included 304 eyes of 224 healthy individuals, divided into 3 groups based on spherical equivalent and axial length: non-myopia, mild-to-moderate myopia, and high myopia. The study measured 10 corneal biomechanical parameters and examined how these were influenced by myopia severity after adjusting for intraocular pressure and corneal thickness.

The findings showed that high myopia was associated with significant changes in corneal biomechanics, including shorter highest concavity time, greater peak distance, and reduced corneal stiffness. These parameters were closely linked to axial length, and the study concluded that as myopia worsens, the cornea becomes progressively less stiff.

The researchers concluded that these biomechanical indicators may help predict scleral strength and could have clinical applications for managing high myopia.

Reference
Sun Y, Guo Y, Pang R, et al. Corneal biomechanical properties and potential influencing factors in varying degrees of myopia. Sci Rep. 2024;14(1):20626. doi: 10.1038/s41598-024-71676-w. PMID: 39232107.